Analysis of the algorithm: From rankings to backup genes.

Ranking section

Table 1. Performance summary for every kernel and net before integration.

Net Kernel tpr_down_ci_0.95 tpr_up_ci_0.95 fpr_down_ci_0.95 fpr_up_ci_0.95 f
genetic_interaction_effect_bicor ct 1 1 1 1 0.896551724137931
genetic_interaction_effect_bicor el 1 1 1 1 0.896551724137931
genetic_interaction_effect_bicor ka 1 1 1 1 0.896551724137931
genetic_interaction_effect_bicor rf 1 1 1 1 0.896551724137931

Table 2. Performance summary for every kernel after integration

Integration Kernel tpr_down_ci_0.95 tpr_up_ci_0.95 fpr_down_ci_0.95 fpr_up_ci_0.95 f
integration_mean_by_presence ct 1 1 1 1 0.909090909090909
integration_mean_by_presence el 1 1 1 1 0.909090909090909
integration_mean_by_presence ka 1 1 1 1 0.909090909090909
integration_mean_by_presence rf 1 1 0.916666666666667 1 0.909090909090909
mean ct 1 1 1 1 0.909090909090909
mean el 1 1 1 1 0.909090909090909
mean ka 1 1 1 1 0.909090909090909
mean rf 1 1 1 1 0.909090909090909

Backup Pairs Coverage By Layer Non integrated

Backup Pairs Coverage By Layer Integrated

Distribution of ranks in dataset by non integrated kernels

Distribution of ranks in dataset by Integrated kernels

ROC-AUCs for Non-integrated kernel and layer

ROC-AUCS for integrated kernels

CDF plots of non integrated kernels

ROC plots of non integrated kernels

ROC plots of integrated kernels

CDF plots of integrated kernels